In Romans 11, Paul writes to the church at Rome about how the salvation available through Christ is offered to everyone: the faithful remnant of Israel (vv. 1-10) and the ingrafted branches of gentiles (vv. 11-24). And the hardened hearts of Israel will be softened so that all will embrace Jesus as Messiah (vv. 25-32). In the concluding verses (vv. 33-36), the apostle can’t help but burst into celebratory song over the wisdom, grace, and power of God.
Chapter 12 is a continuation of his reasoning. It begins with the word therefore, which is a classic literary signal that what’s coming is the result of what was said previously. Because God offers salvation to so many and because His wisdom is beyond scrutiny, those who’ve chosen Jesus should offer themselves as living sacrifices (v. 1), renew their minds so they’re not conformed to this world (v. 2), and be humble (v. 3).